First Author, Year	Design	Setting/Country	Population	Intervention	Outcomes	Follow-up Duration
Balán et al, 2019[@97847]	Cross- sectional pilot study	New York, USA	Men, transgender women- men who have sex with men	SMARTtest: A Smartphone App to Facilitate HIV and Syphilis Self and Partner‑Testing, Interpretation of Results, and Linkage to Care	App assisted use of the HIVST kits provided self-reported test results	NA
Tun et al, 2018 [@97864]	Cohort study	Lagos, Nigeria	men who have sex with men, (17-59) years	Using key opinion leaders to reach men who have sex with men with HIVST kits	Use of the HIVST kits provided and their experience	3 months
Sibanda et al, 2019[@97866]	Discrete Choice Experiment	2 rural districts, Zimbabwe	Men and women ≥16 years old (mean age 37.10)	Door-to-door HIVST kits distribution by community volunteers	Method of HIVST kits distribution preferences.	NA
Phanuphak et al, 2019[@97865]	Cohort study	Bangkok Metropolitan Thailand	men who have sex with men and transgender workers	Online, supervised, HIV self-testing.	HIV testing preference and experience, linkage to care	12 months
Shapiro et al, 2020[@97855]	RCT	Kwa Zulu Natal, South Africa	Adult men Median Age (28)	Lay counsellors distributed HIVST kits, conducted a live demonstration of how to use and interpret both test kits, and provided cell-phone videos demonstrating kit use,	Reported HIVST, linkage to care	3 months
MacPherson et al, 2014[@97862]	RCT	Blantyre, Malawi	Adult male and female (16 years and above)	Optional Home Initiation of HIV Care Following HIV Self-testing	Cumulative incidence of ART initiation, accepting HIV self-testing kit, reporting a positive HIV self-test result to counsellors	6 months
Korte et al, 2020[@97857]	RCT	Peri urban Hospitals Uganda	Male partners of women attending ANC. Age (yr), mean (25.2)	provided women with education and up to 4 HIVST kits to deliver to their male partners and other adults in the household.	Woman’s self-report of male partner HIV testing, man’s self-report, and measure combining self-report from both partners	3 months
Zhong et al, 2017[@97863]	Cross-sectional survey	Guangzhou, China	males 18 years men who have sex with men	Social-Entrepreneurship Model to Promote HIV Self-testing and linkage to care among men who have sex with men	Prevalence of HIVS kits use, linkage to care frequency	1 month
Pai et al, 2018[@97846]	Cross-sectional study	Montreal, Canada	18 years or older, self-identified as men who have sex with men	Unsupervised Smart App–Optimized HIV Self-Testing Program	self-test conduct; self-test interpretation; and linkages to care	NA
Choko et al, 2015[@97856]	RCT	Blantyre, Malawi	Adults (>16 y old) residents	comparing health outcomes between 14 clusters randomised to HIVST and 14 clusters randomised to routine (facility-based) HTC	Uptake of testing, accuracy, linkage into care,	2 years
Chanda et al, 2017[@97858]	RCT	Kapiri Mposhi, Chirundu, and Livingstone, Zambia	18 years of age or older men who have sex with men	Peer educators distributed 2 HIV self-test kits plus instructions on its use	Actual use of the HIV self-tests, self-report their HIV status at the 4-month visit.	4 months
Ortblad et al, 2017[@97859]	RCT	Kampala, Uganda,	18 years or older, FSWs	Direct provision, facility collection of HIV self-tests versus standard of care	intimate partner violence (IPV), HIV self-test use and linkage to care	4 months
Choko et al, 2019[@97860]	RCT	Blantyre, Malawi	women attending antenatal care	HIV self-testing alone or with additional interventions, including financial incentives and linkage to care	Proportion of male partners who tested for HIV and linked into care	1 month
Zhang et al, 2019[@97861]	Pragmatic trial	China	Men who have sex with men	HIV Self-Testing Programs to men who have sex with men delivered by Social Media Key Opinion Leaders and Community-Based Organizations	Number of HIVST respondents recruited by each investigator in SMKOL-strategy and CBO strategy	1 year