Bias categories§
Ref Author, Year Country Primary setting‡ Age range Assessment → Outcomes reported 1 2 3 4 5 6
[@30505] Araya S, 2016 Paraguay Inpatient 1m - 17y CXR finding/ (absence of) fever/ hypoxia/ tachypnoea → death
[@30534] Coarasa A, 2010 Argentina Emergency 1 - 24m Argentinian respiratory distress scale/ Chilean respiratory distress scale --> hypoxia
Chest indrawing --> hypoxia†
[@30541] le Roux DM, 2015 South Africa Outpatient 0 - 11m Chest indrawing/ fever/ hypoxia /tachypnoea → inpatient admission
[@30542] Lum LC, 2011 Malaysia PICU 0 - 59m Tachypnoea → mechanical ventilation
[@30543] Mesquita M, 2009 Paraguay Emergency 1 - 59m Higher Respiratory Distress Assessment Instrument (RDAI) scores → hospital admission
[@30548] Nathan AM, 2014 Malaysia Inpatient 1m - 17y Hypoxia → risk of life threatening disease†
[@30507] Reed C, 2012 South Africa Inpatient 1 - 59m Hypoxia/ chest indrawing/ intercostal retractions/ wheezing/ tachypnoea → death†
[@30552] Vidaurreta SM, 2011 Argentina Inpatient 1 - 59m Cyanosis/ retractions/ tachypnoea/ wheezing → hospital admission†
[@30553] Vilas-Boas AL, 2014 Brazil Inpatient 1 - 59m Fever†/ chest retractions/ tachypnoea†/ wheezing† → treatment failure
Crackles → (decreased) treatment failure†
[@30506] Zhang Q, 2013 China PICU 1 - 59m Wheezing → (decreased) death/ (decreased) length of PICU stay/ (decreased) mechanical ventilation
Head nodding → mechanical ventilation/ death
Cyanosis/ grunting or groaning/ hypoxia/ tachypnoea → prolonged PICU stay/ mechanical ventilation/ death