Bias categories§
Ref Author, Year Country Primary setting‡ Age range Assessment → Outcomes reported 1 2 3 4 5 6
[@30524] Acacio S, 2015 Mozambique Outpatient 1 - 59m Crepitations or rales/ fever/ wheeze or rhonchi → referral from peripheral health center to district hospital outpatient department†
Crepitations or rales†/ Nasal flaring → referral to emergency department†
[@30530] Basnet S, 2015 Nepal Inpatient 1 - 59m CXR finding/ Hypoxia --> increased time to recovery of illness†/ treatment failure†
[@30531] Bassat Q, 2008 Mozambique Inpatient 1 - 59m Chest indrawing → death†
[@30495] Bassat Q, 2016 Mozambique Inpatient 0 - 59m Hypoxia → prolonged admission/ death
Chest indrawing/ CXR finding/ cyanosis†/ grunting/ nasal flaring/ tachypnoea†/ thoracoabdominal breathing† → hypoxia
[@30536] Graham SM, 2011 Malawi Inpatient 1m - 17y Hypoxia → death
[@30539] John BM, 2015 Nepal NICU Preterm - 1m Downe's score/ hypoxia → death/ increased frequency of respiratory support at 72 hours of age/ mechanical ventilation
[@30540] King C, 2016 Malawi Outpatient 1 - 59m Hypoxia → non-recovery at day 5†
[@30486] Kuti BP, 2013 Gambia Inpatient 1 - 59m Cyanosis†/ grunting†/ head nodding → hypoxia
[@30487] Kuti BP, 2013 Gambia Inpatient 1 - 59m Grunting/ hypoxia → death
[@30488] Kuti BP, 2014 Gambia Inpatient 1 - 59m Grunting/ head nodding → prolonged hospital stay
[@30496] McCollum ED, 2013 Malawi Inpatient 0m - 17y Chest indrawing/ nasal flaring/ tachypnoea → hypoxia
[@30546] Nantanda R, 2008 Uganda Inpatient 1 - 11m Grunting/ hypoxia → death
[@30547] Nantanda R, 2014 Uganda Inpatient 1 - 59m Hypoxia → death† / prolonged hospital stay
[@30550] Ramakrishna B, 2012 Malawi Inpatient 1m - 17y Hypoxia → death
[@30551] Sigauque B, 2009 Mozambique Inpatient 0 - 59m Crepitations → (decreased) death
Wheezing/rhonchi → death
[@30497] Wandeler G, 2015 Senegal Inpatient 1 - 59m Cyanosis†/ nasal flaring/ tachypnoea/ → hypoxia
Chest-indrawing/ grunting → hypoxia*