de Jager et al., 2017[@17310] |
Dementia prevalence in a rural region of South Africa: a cross-sectional community study |
A total of 1,394 Xhosa-speaking community dwellers |
Mean age ±SD 71.3 ± 8.3 y |
Diagnosis and prevalence |
Using a published CSID sensitivity/specificity values the prevalence estimate was 0.8 (95% CI=0.06-0.09). Using CSID cut-off scores the estimated prevalence was 0.12 (95% CI=0.10-0.13), with 161 screen-positives. |
Dewhurst et al., 2013[@17311] |
The prevalence of neurological disorders in older people in Tanzania |
A total of 2232 individuals from rural Hai district |
70 years and above |
Diagnosis and prevalence |
Results show that the age-adjusted prevalence of people with neurological diagnoses was 154.1 per 1000 (95% CI=139.2-169.1). The age-adjusted prevalence per 1000 of the most common neurological disorders were tremor (48.2), headache (41.8), stroke (23.0), peripheral polyneuropathy (18.6), upper limb mononeuropathy (6.5) and parkinsonism (5.9). |
Guerchet et al., 2013[@17312] |
Comparison of rural and urban dementia prevalence in two countries of Central Africa: The EPIDEMCA Study |
A total of 2004 elderly were interviewed in Central African Republic (CAR) and Republic of Congo |
Participants aged ≥65 years old |
Diagnosis and Prevalence |
Preliminary analysis showed a DSM-IV dementia prevalence at 8.8% (95% CI=6.4-11.8) in Nola and at 6.0% (95% CI: 4.1-8.4) in Bangui. |
Longdon et al., 2013[@17313] |
The prevalence of dementia in rural Tanzania: a cross-sectional community-based study. |
A total of 1198 People from rural Hai district |
Participants were 70 years and older |
Diagnosis and Prevalence |
Analysis of the data showed that 184 screened positive for probable dementia, and 104 screened positive for possible dementia using the Community Screening Instrument for Dementia. Following clinical assessment, 78 cases of dementia were identified according to the DSM-IV criteria. The age-standardised prevalence of dementia was 6.4% (95% CI=4.9-7.9). Prevalence rates increased significantly with increasing age. |
Pellegrini et al., 2018[@17314] |
Machine learning of neuroimaging for assisted diagnosis of cognitive impairment and dementia: A systematic review. |
Not applicable (NA) |
NA |
Diagnosis and Prevalence |
Systematic analysis of the data showed that accuracy was highest for differentiating Alzheimer's disease from healthy controls and not good for differentiating healthy controls versus mild cognitive impairment |
Ngandu et al., 2015[@17315] |
A 2-year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial |
A total 2654 individuals |
Participants were 60-77 years |
Prevention of dementia |
Findings from this large, long-term, randomised controlled trial suggest that a multidomain intervention could improve or maintain cognitive functioning in at-risk elderly people from the general population |
Mangialasche et al., 2012[@17316] |
Dementia prevention: current epidemiological evidence and future perspective |
NA |
NA |
Prevention of dementia |
Evidence suggest that prevention of dementia is moving from observational to interventional studies to verify hypotheses and define tools that can be applied in the general population. Since a cure for dementia is not yet available, finding effective preventive strategies is essential for a sustainable society in an aging world. |
Andrade and
Radhakrishnan, 2009[@17317] |
The prevention and treatment of cognitive decline and dementia: An overview of recent research on experimental treatments |
NA |
NA |
Prevention of dementia |
Analysis of epidemiological studies suggest that dietary measures, physical exercise, and mental activity may reduce the risk of cognitive impairment and Alzheimer's disease in elderly subjects. Statins may protect against incident dementia. |
Clarke and Bailey, 2016[@17301] |
Narrative citizenship, resilience and inclusion with dementia: On the inside or on the outside of physical and social places |
Families living at home with dementia and interviews with service providers and commissioners (a total of 57 diaries, 69 interviews with people living with dementia and 6 interviews with service providers and commissioners) |
NA |
Advocacy – understanding of living with dementia |
Familiarity with people and place was seen to be supportive of inclusion and feeling on the inside. |